1 glas alcohol per dag verlaagt hart- en vaatziekten met 14-25%

Research Question:
Moderate alcohol drinking lowers the chances of getting heart disease?

Study Design:
This overview article contained 84 prospective cohort studies with an average follow-up period of 11 years (2.5 to 35 years). 15% of the studies had a follow-up duration of 5 years or shorter. 40% of these 84 studies were studies with only men, 7% with only women and 52% with both men and women in it.

Results and conclusions:
The researchers found in 21 studies that drinking alcohol compared with not drinking, the chances of death to cardiovascular diseases significantly with reduced 25% [95% CI = 0.70-0.80]. Significant is, there can be with 95% reliability said that drinking alcohol the chance of death to cardiovascular diseases reduced by 25%.

The researchers found that drinking alcohol in 10 studies compared with not drinking, the chances of dying from stroke non-significant increased by 6% [95% CI = 0.91-1.23]. Non-significant is, there is no link to a 95% reliability.

The researchers found that drinking alcohol in 31 studies compared with not drinking, the risk of dying from coronary heart diseases significantly reduced by 25% [95% CI = 0.68-0.81].

In dose-dependent analyses, the researchers found that the risk of dying from coronary heart diseases was the lowest at 1-2 glasses a day and for the risk of dying from stroke was that at the 1 glass or less per day.

In the secondary analyses of 84 studies researchers found that drinking alcohol compared with not drinking, the chance to die to all causes (all-cause-mortality) significantly with 13% [95% CI = 0.83-0.92] reduced.

In the secondary analyses of 8 studies the researchers found that drinking more than 60 grams of alcohol per day the chance to die of all causes (all-cause-mortality) significantly with 30% [95% CI = 1.22-1.38] increased.

The researchers concluded that drinking 2.5-14.9 grams of alcohol per day (about 1 drink per day) the chance of getting heart disease with 14-25% reduced.

Original title:
Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis by Brien Ronksley PE, SE, [...], Ghali WA.

Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043109/pdf/bmj.d671.pdf

Additional information about El Mondo:
Read more about alcohol in the presentation flavonoids.