Voedingsadvies El MondoResearch Question:
The association between the intake of magnesium through diet and the risk of getting colorectal cancer (colon cancer) is in many prospective studies examined, but it remains controversial because of inconsistent results. It was therefore carried out this review article.
Eating magnesium lowers the chances of getting colon cancer?
Study Design:
This overview article contained 7 prospective cohort studies until June 2012 with 333510 participants, of which 7435 patients with colon cancer.
Results and conclusions:
The researchers found that eating a lot of magnesium compared with little magnesium, the chances of getting colon cancer significantly with 19% [95% CI = 0.70-0.92] reduced. Significant is, there is a link at a 95% reliability.
The researchers found that eating a lot of magnesium compared with little magnesium, the chances of getting colon cancer in women significantly with 19% [95% CI = 0.68-0.94] reduced. Significant is, there is a link at a 95% reliability.
The researchers found that eating a lot of magnesium compared with little magnesium, the chances of getting colon cancer in men with non-significant 24% [95% CI = 0.51-1.01] reduced. Non-significant is, there is no link to a 95% reliability.
The researchers found a non-linear relationship between magnesium intake via diet and reduced risk of getting colon cancer. The reduced risk was the largest at 200-270 mg of magnesium per day.
The researchers concluded that eating 200-270 mg of magnesium per day the chances of getting colon cancer, especially in women reduced.
Original title:
Nonlinear association between magnesium intake and the risk of colorectal cancer by Xinhua Fangchun Q, J, [...], Kerong D.
Link:
http://journals.lww.com/eurojgh/Abstract/2013/03000/Nonlinear_association_between_magnesium_intake_and.7.aspx
Additional information about El Mondo:
Read more about magnesium.
Colorectal cancer almost always arises from a polyp. A dikkedarmpoliep is an overgrowth of the lining of the colon. Most polyps are benign tumors and will continue too. Only in a small percentage polyps come "troubled cells" for. When malignant cells grow in the wall of the colon, we speak of colorectal cancer.
Most of the tumors (50 to 60%) originates in the last parts of the colon: the sigmoid and rectum.
Colon cancer occurs mainly in people of 60 years of age and older. But colon cancer can also occur on (much) younger age. At 5 to 10% of patients with colon cancer there is heredity.
Colon cancer occurs slightly more often in men than in women.