200 microgram foliumzuur per dag verlaagt hart- en vaatziekte

Research Question:
Epidemiological studies are inconsistent with respect to the relationship between the intake of folic acid and reduced risk of heart disease. It was therefore carried out this review article.

The consumption of folic acid reduces the risk of cardiovascular disease?

Study Design:
This overview article contained 14 prospective cohort studies to August 2010. 7 studies looked at the folic acid intake via diet and 8 to the levels of folic acid in the blood.

Results and conclusions:
The researchers found that eating a lot of folic acid compared with little, chances of getting heart disease significantly with 31% [95% CI = 0.60-0.80] reduced. Significant is, there is a link at a 95% reliability.

The researchers found that eating 200 micrograms of folic acid per day the chance of getting heart disease significantly with 12% [95% CI = 0.82-0.94] reduced. Significant because the risk of 1 was not in the 95% CI of 0.82-0.94. Risk of 1 is, there is no raised or lowered risk.

The researchers found that the highest blood folate levels the chance of getting heart disease non-significant 26% [95% CI = 0.53-1.02] reduced. Non-significant because the risk of 1 sat in the 95% CI of 0.53-1.02.

The researchers found that every increase in blood folate levels with 5 mmol/l the chance of getting heart disease non-significant with 8% [95% CI = 0.84-1.00] reduced. Non-significant is, there is no link to a 95% reliability but a trend.

The researchers concluded that eating 200 micrograms of folic acid per day or more chances of getting heart disease reduced.

Original title:
Folate and risk of coronary heart disease: A meta-analysis of prospective studies by Wang ZM, Zhou B, [...], Wang LS.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/21924595

Additional information about El Mondo:
Read more about folic acid.

This meal delivers 200 micrograms of folic acid.