240 mg magnesiumsupplementen per dag verlaagt de bovendruk

Research Question:
Is there a dose-dependent relationship between swallowing magnesium supplements and lowering blood pressure?

Study Design:
This overview article contained 20 Rcts (16 with hypertensive and 6 with normotensieve participants) with a total of 1220 participants.

The dosage of magnesium supplements in the studies ranged from 10 to 40 mmol/day with an average of 15.4 mmol per day or 370 mg of magnesium per day.

Results and conclusions:
The researchers found that taking magnesium supplements with 0.6 mmHg systolic blood pressure not significant [95% CI =-2.2 to 1.0] and the diastolic blood pressure is not significantly with 0.8 mmHg [95% CI =-1.9 to 0.4] reduced.

However, the researchers found a dose-dependent relationship between swallowing magnesiumssuplementen and lowering blood pressure. They found that each 10 mmol (240 mg) magnesium supplements per day, the systolic blood pressure significantly with 4.3 mmHg [95% CI = 6.3 to 2.2, p 0.001] and the diastolic blood pressure not significant with 2.3 mmHg [95% CI = 4.9 to 0.0, p = 0.09] reduced.
Significant is, there is a link at a 95% reliability.

The researchers concluded that a dose-dependent relationship existed between taking magnesium supplements and lowering blood pressure, especially the systolic blood pressure (systolic blood pressure).

Original title:
The effect of magnesium supplementation on blood pressure: a meta-analysis of randomized clinical trials by Jeea SH, Miller THERE, [...], Klagb MJ.

Link:
http://www.sciencedirect.com/science/article/pii/S0895706102029643

Additional information about El Mondo:
Read more about high blood pressure.