Voedingsadvies El MondoResearch Question:
Existing epidemiological evidence is controversial on the possible links between coffee consumption and the risk of getting the aggressive forms of prostate cancer. It was therefore carried out this review article.
Drinking coffee lowers the chances of getting the aggressive forms of prostate cancer?
Study Design:
This overview article contained 3 case-control studies and 5 cohort studies with 406718 participants together.
There was no question of publication bias.
The heterogeneity was low (I2 = 0-26%).
Results and conclusions:
The researchers found (6 studies with 5733 people with low-grade prostate cancer) that every 3 cups of coffee a day, the chance of getting low-grade prostate cancer not significantly with 3% [RR = 0.97, 95% CI = 0.92-1.03] reduced.
The researchers found (6 studies with 1965 people with high-grade prostate cancer) that every 3 cups of coffee a day, the chance of getting high-grade prostate cancer non-significant 11% [RR = 0.89, 95% CI = 0.78-1.00] reduced.
The researchers found (6 studies with 25188 people with localized prostate cancer) that every 3 cups of coffee a day, the chances of getting localized prostate cancer significantly with 3% [RR = 0.97, 95% CI = 0.94-0.99] reduced.
The researchers found (6 studies with 5724 people with advanced prostate cancer) that every 3 cups of coffee a day, the chances of getting advanced prostate cancer does not significantly with 5% [RR = 0.95, 95% CI = 0.85-1.06] reduced.
The researchers found in 4 studies that each 3 cups a day, the chances of getting fatal prostate cancer significantly with 11% [RR = 0.89, 95% CI = 0.82-0.97] reduced.
The researchers found in 4 studies that each 3 cups a day, the chances of getting prostate cancer with a Gleason score of 8-10 significantly with 16% [RR = 0.84, 95% CI = 0.72-0.98] reduced.
The researchers concluded that drinking 3 cups of coffee per day the chances of getting fatal prostate cancer reduced.
Original title:
Coffee consumption and risk or nonaggressive, aggressive and fatal prostate cancer--a dose-response meta-analysis by Discacciati A, Orsini N and Cloud A.
Link:
http://annonc.oxfordjournals.org/content/early/2013/11/22/annonc.mdt420.full
Additional information about El Mondo:
Find here more studies on prostate cancer and drinking coffee.