600-900 mg knoflooksupplementen per dag verlaagt de bloeddruk

Research Question:
Swallowing garlic supplements lowers the blood pressure?

Study Design:
This overview article contained 11 Rcts to October 2007. The dosages of the garlic supplements ranged from 3.6 to 5.4 mg of allicin per day or 600-900 mg. The duration of 7 of the 11 studies was 12 weeks.
There was no publication bias.

Results and conclusions:
The researchers found that people who took garlic supplements compared with people who had no garlic supplements had to allow a significant reduction in systolic blood pressure, with the 4.6 mmHg [± 2.8 mmHg, p = 0.001]. Significant is, there is a link at a 95% reliability.

The researchers found that people with high blood pressure who took garlic supplements compared with people who had no garlic supplements had to allow a significant reduction of the peak pressure, with 8.4 mmHg [± 2.8 mmHg, p 0.001] and a significant reduction in the vacuum with 7.3 mmHg [± 1.5 mmHg, p 0.001].

The researchers concluded that taking garlic supplements (600-900 mg daily) reduced blood pressure, especially in people with high blood pressure.

Original title:
Effect of garlic on blood pressure: A systematic review and meta-analysis by Frank Ried K, OR, [...], Sullivan t.

Link:
http://www.biomedcentral.com/content/pdf/1471-2261-8-13.pdf%20%28

Additional information about El Mondo:
Garlic contains 33 sulfur-containing compounds. Allicin is considered to be the most important bioactive sulfur compound in garlic. When garlic is chopped or crushed, put the enzyme allinase (present in garlic) Tasha (present in intact garlic) into allicin. The typical smell of garlic comes from the breakdown products of allicin.

Tasha 1 mg is equal to 0.45 mg allicin. 1 gram of garlic delivers 2.5-4.5 mg allicin. So a clove of garlic by 2 grams delivers 5-9 mg of allicin. So 3.6 mg allicin corresponds to 0.8-1.44 grams of garlic and 5.4 mg of allicin is equivalent to 1.2-2.2 grams of garlic.