Dagelijks 50 mg magnesium via voeding verlaagt het nuchter glucose- en insulinegehalte

Research Question:
Eating a lot of magnesium lowers the fasting glucose and insulin levels?

Study Design:
This overview article contained 15 CHARGE participants of European cohort studies with 52684 descent without diabetes.
The fixed-effects model was used.

Results and conclusions:
The researchers found after having corrected for age, sex, energy intake, BMI and behavioral risk factors, that each increase with 50 mg of magnesium per day the fasting glucose levels significantly with 0.009 mmol/L [β =-0.009 mmol/L, 95% CI =-0.013 to-.005, p 0.0001] reduced. Significant is, there is a link at a 95% reliability.

The researchers found after having corrected for age, sex, energy intake, BMI and behavioral risk factors, that each increase with 50 mg of magnesium per day the fasting insulin levels significantly with 0.020 In-pmol/L [β =-0.020 ln-pmol/L, 95% CI =-0.024 to-0.017, p 0.0001] reduced.

The researchers found that single-nucleotide polymorphism and magnesiumgerelateerde the interaction between single nucleotide polymorphism and magnesium reached no significance after adjusting for multiple failure factors.

The researchers concluded that high magnesium intake (minimum 50 mg per day) through feeding the fasting glucose and insulin levels reduced.

Original title:
Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies by Hruby A, Ngwa JS, [...], Nettleton Yes.

Link:
http://jn.nutrition.org/content/143/3/345.short

Additional information about El Mondo:
This meal delivers 170 mg of magnesium.

Patients with type 2 diabetes have high fasting glucose and insulin levels.