Een vitamine D-bloedwaarde lager dan 50 nmol/L tijdens de zwangerschap verhoogt pre-eclampsie, zwangerschapdiabetes, een vroeggeboorte en een SGA-baby

Research Question:
Increases low vitamin D blood value during pregnancy the chance of getting preeclampsia, gestational diabetes, a premature birth or a SGA baby?

Study Design:
This overview article contained 24 observational studies.

Results and conclusions:
The researchers found that a vitamin D blood value is less than 50 nmol/L during pregnancy, the chances of getting preeclampsia (pregnancy toxaemia) significantly with 109% [95% CI = 1.50-2.90] increased. Significant is, there is a link at a 95% reliability.

The researchers found that a vitamin D blood value is less than 50 nmol/L during pregnancy, the chances of getting gestational diabetes significantly with 38% [95% CI = 1.12-1.70] increased.

The researchers found that a vitamin D blood value is less than 50 nmol/L during pregnancy, the chances of getting a premature birth significantly with 58% [95% CI = 1.08-2.31] increased.

The researchers found that a vitamin D blood value is less than 50 nmol/L during pregnancy, the chances of getting an SGA baby significantly with 52% [95% CI = 1.08-2.15] increased.

The researchers concluded that a vitamin D blood value is less than 50 nmol/L during pregnancy the chance of getting preeclampsia, gestational diabetes, a premature birth and SGA baby increased.

Original title:
Maternal vitamin D status and adverse pregnancy outcomes: a systematic review and meta-analysis by Wei SQ, Qi HP, [...], Fraser WD.

Link:
http://informahealthcare.com/doi/abs/10.3109/14767058.2013.765849?journalCode=jmf

Additional information about El Mondo:
Read more about studies on vitamin d.