Voeding en gezondheid

200-1000 mg vitamine C per dag verlaagt de oxidatieve stress

Research Question:
How many mg of vitamin C per day is needed to reduce the increased oxidative stress among athletes?

Study Design:
This overview article contained 12 studies. They were crossover or Rcts. The vitamin C supplementation period ranged from acute to 5 months.

 

Results and conclusions:
Antioxidants supplements are widely used by athletes in order to avoid the increased oxidative stress. The increased oxidative stress leads to muscle damage, a lowered immune system and fatigue.

The researchers conclude that 200-1000 mg of vitamin C per day reduces the oxidative stress while more than 1000 mg per day seems to reduce the training-induced adaptations by decreasing the mitochondrial biogenesis or by any changes of the vascular function.

200 mg of vitamin C per day, obtained by five servings of fruits and vegetables, may be enough to reduce the oxidative stress without the threshold adjustments to exceed the optimal training harms.

During periods of increased oxidative stress athletes can benefit from swallowing more than 200 mg of vitamin C per day for 1 to 2 weeks.

Original title:
Effect of Vitamin C Supplements on Physical Performance by Ballard AJ.

Link:

http://journals.lww.com/acsm-csmr/Fulltext/2012/07000/Effect_of_Vitamin_C_Supplements_on_Physical.8.aspx

Additional information about El Mondo:
Oxidative stress is caused by an imbalance between pro-oxidants and antioxidants. This imbalance can be caused by an increased level of reactive oxygen particles and/or reactive nitrogen particles or a decrease in antioxidant in the immune system. Antioxidants include vitamin C, E, zinc, beta carotene and flavonoids. Pro-oxidants include exhaust fumes, cigarette smoke, particulate matter.

 

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Research questio
n: Studies on the relationship between diabetes and hepatocellular carcinoma (primary liver cancer) gave inconsistent findings on. It was therefore carried out this review

article.Diabetes increases the risk of hepatocellular carcinoma?Study design:

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ts and conclusions: th
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The meta-analysis also showed that diabetics 2.43 times more likely [RR = 2.43, 95% CI = 1.66-3.55] walked, dying to hepatocellular carcinoma than those without diabetes.

The researchers concluded that the chance of getting diabetes both hepatocellular carcinoma as dead to hepatocellular carcinoma increased.Original

title: Diabetes mel
litus and risk or hepatocellular carcinoma: a systematic review and meta-analysis by Wang P, Kang DH, [...], Liu Z.

Lin
k: http://onlinelibrary.wiley.com/doi/10.1002/dmrr.1291/abstract?deniedAccessCustomisedMessage=&userIsAuthent

icated=falseExtra informati
on of El Mondo: HCC or primary liver cancer is very rare in the Western world a malignant tumor, but the most frequent primary malignant liver tumor. Hepatocellular carcinoma is one of the most common malignant diseases.The main caus
es of primary liver cancer are hepatitis B, C and D, alcoholic liver cirrhosis, metabolic liver diseases (such as hemochromatosis and alpha1-antitrypsin deficiency) and non-alcoholic steatohepatitis.More t
han 80% of patients with hepatocellular carcinoma has cirrhosis of the liver.