Voedingsadvies El MondoResearch Question:
Long chain polyunsaturated fatty acids (LC-PUFA) would be beneficial in preventing pancreatic cancer, but the relationship between the consumption of fish or LC-PUFA and pancreatic cancer found in epidemiological studies is controversial and inconclusive. It was therefore carried out this review article.
Eating fish or LC-PUFA lowers the chances of getting pancreatic cancer?
Study Design:
This overview article contained 9 cohort studies with 1209265 participants, of which 3082 people with pancreatic cancer and an average follow-up period of 9 years. This review article also contained further 10 case-control studies with 2514 patients with pancreatic cancer and 18779 controls (people without pancreatic cancer).
Results and conclusions:
The researchers found in 8 cohort studies that compared with the lowest fish consumption, the highest fish consumption the chance of getting pancreatic cancer non-significant with 2% [RR = 0.98, 95% CI = 0.86-1.12] reduced. Non-significant is, there is no link.
The researchers found in 9 cohort studies that compared with the lowest fish consumption, the highest fish consumption the chance of getting pancreatic cancer non-significant 4% [RR = 0.96, 95% CI = 0.76-1.21] reduced. Non-significant is, there is no link.
Similar results were also found for LC-PUFA in 4 cohort studies and case-control studies 2.
The researchers concluded that there is no link existed between eating fish or LC-PUFA and the chance of getting pancreatic cancer.
Original title:
Fish or Long-Chain (n-3) PUFA Intake Is Not Associated with Pancreatic Cancer Risk in a Meta-Analysis and Systematic Review by Qin B, Xun P and Hey K.
Link:
http://jn.nutrition.org/content/142/6/1067.short
Additional information about El Mondo:
Read more about LC-PUFA in the presentation fats.
Why the result found in cohort studies always lower than in case-control studies can be read in the presentation design.