Vitamine C-supplementen verlagen op korte termijn de bloeddruk

Research Question:
In observational studies, an increased intake of vitamin C, vitamin C supplementation and high vitamin C blood concentration are associated with low blood pressure. But the instructions for blood pressure-lowering effects of vitamin C in clinical studies have been inconsistent. Therefore it was the aim of this systematic review and meta-analysis of clinical trials to the effects of vitamin C supplementation on blood pressure to investigate.

Can vitamin C supplements lower blood pressure?


Study Design:
This overview article contained 29 Rcts with an average duration of 8 weeks and 10 to 120 participants per study. Only Rcts can show a causal link.

Results and conclusions:
The researchers found that taking vitamin C supplements (on average 500 mg per day) the systolic pressure (systolic blood pressure) significantly with 3.84 mmHg [95% CI =-5.29 to-2.38 mm Hg, p 0.01] did decrease. Significant is, it can be said with 95% reliability that the short-lived swallowing vitamin C supplements reduced the peak pressure really.

The researchers found that taking vitamin C supplements (on average 500 mg per day) the diastolic pressure (underpressure) significantly with 1.48 mmHg [95% CI =-2.86 to-0.10 mmHg, p = 0.04] did decrease. Significant because the p-value was less than 0.05.

Methypertensieve participants in studies the researchers found that taking vitamin C supplements (on average 500 mg per day) the systolic pressure significantly with 4.85 mmHg [p 0.01] did decrease.


Methypertensieve participants in studies the researchers found that taking vitamin C supplements (on average 500 mg per day) the diastolic pressure non-significant with 1.67 mmHg [p 0.17] did decrease. Non-significant means no link.

The researchers concluded that the short-lived swallowing vitamin C supplements (500 mg per day with an average duration of 8 weeks) the blood pressure lowered but research is needed into the effect of the prolonged swallow vitamin C supplements on blood pressure.

Original title:
Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials by Juraschek SP, Guallar E, [...], Miller THERE.

Link:

http://www.ajcn.org/content/95/5/1079.short

Additional information about El Mondo:
The optimal blood pressure for a healthy adult person is 120 mmHg systolic blood pressure and 80 mmHg vacuum.


It is not possible through feeding 500 mg of vitamin C per day to get inside. 200-300 g of vegetables and 2-5 pieces of fruit per day on average 200 mg vitamin C on.