Voedingsadvies El MondoResearch Question:
Studies in people and animals suggest that zinc has the potential to affect the metabolism of cholesterol and thereby affects the risk of cardiovascular diseases.
Zinc supplements decrease chances of getting heart disease?
Study Design:
This contained 20 Randomized placebo-controlled, double-blind overzichtartikel, intervention studies (Rcts) with 14238 participants.
Results and conclusions:
The meta-analysis showed that swallowing zinc no significant effect on the plasma total cholesterol, LDL-cholesterol, HDL-cholesterol or plasma triglycerides concentration had. No significance is, there is no link to a 95% reliability.
However, secondary analysis in healthy participants showed that swallowing zinc plasma HDL cholesterol significantly with 0.10 mmol/L [± 0.02 mmol/L, p = 0.001, n 13215] reduced, which corresponded to a reduction of 7% compared to the initial value.
The researchers found that the zinc plasma zinc concentration swallowing significantly with 2.42 micromol/L [± 0.25 μmol/L, p = 0.001; n 14047] increased.
The researchers concluded that swallowing of zinc the zinc concentration in the body increased, while reduced HDL cholesterol in healthy persons and thus contributed to an increased chance of getting heart disease.
Original title:
Effects of zinc on plasma lipoprotein cholesterol concentrations in humans: A meta-analysis of randomized controlled trials by Fostera M, Petoczb P and Sammana S.
Link:
http://www.sciencedirect.com/science/article/pii/S0021915009009952
Additional information about El Mondo:
Read more about zinc.
Swallow only nutritional supplements when the claim has been approved by EFSA or when a protective effect is found in review articles of Rcts.