Alcohol verhoogt niet hersenkanker

Research Question:
Alcohol may pass blood brain barrier and is therefore a possible risk factor for brain cancer. Several epidemiological studies have been published on this subject with however inconsistent findings. It was therefore carried out this review article.

Drinking alcohol increases the chance of getting brain cancer?

Study Design:
This overview article contained 19 epidemiological studies.

Results and conclusions:
The researchers found in a pooled analysis of 12 studies that alcohol consumption compared with no alcohol consumption, the chance of getting brain cancer non-significant with 3% [95% CI = 0.82-1.15] reduced. Non-significant is, there is no link to a 95% reliability.

The researchers found in a pooled analysis that drinking less than 2 drinks per day compared to without alcohol consumption, the chance of getting brain cancer non-significant with 1% [95% CI = 0.81-1.25] increased. Non-significant is, there is no link to a 95% reliability.

The researchers found in a pooled analysis that drinking more than 2 drinks per day compared to without alcohol consumption, the chance of getting brain cancer non-significant with 35% [95% CI = 0.85-2.15] increased. Non-significant is, there cannot be said with 95% reliability, that drinking more than 2 drinks per day the chance of getting brain cancer increased by 35%.

The subgroup-analyses (to get more information) showed that the consumption of wine compared to without consumption, the chance of getting brain cancer non-significant with 1% [95% CI = 0.70-1.48] increased.
For beer was a non-significant reduction of 4% [95% CI = 0.82-1.12] and for spiritus was a significant increase of 20% [95% CI = 1.01-1.42].

The researchers found that alcohol consumption compared with no alcohol consumption, the chance of getting glioma non-significant with 7% [95% CI = 0.81-1.07] reduced.

The researchers found that alcohol consumption compared with no alcohol consumption, the chance of getting Meningioma non-significant 29% [95% CI = 0.45-1.12] reduced.

The researchers concluded that drinking alcohol, except for spiritus the chance of getting brain cancer not increased.

Original title:
A meta-analysis of alcohol consumption and the risk of brain tumours by Galeone C, Malerba S, [...], Pelucchi C.

Link:
http://annonc.oxfordjournals.org/content/24/2/514.short

Additional information about El Mondo:
The two malignant brain tumors are glioma and Meningioma. Brain cancer can arise from malignant brain tumors.

The low grade glioma mainly occurs in people between 20 and 40 years. The high-grade glioma occurs mainly in people over 40 years. A Meningioma occurs most frequently in people over 40 years.

Read more about alcohol in the presentation flavonoids.