Dagelijks 330 ml melk verlaagt botverlies

Research Question:
Lowers drinking milk bone loss?

Study Design:
This overview article contained 11 Rcts to november 2010 with 2397 participants. There was no publication bias.
The quantity of milk in most studies was 330 ml per day.

Results and conclusions:
The researchers found that the osteocalcinegehalte in people who drank milk compared with people who drank no milk, significantly with 5.9 ng/ml [95% CI =-7.23 to-4.57] reduced. Significant is, there is a link at a 95% reliability.

The researchers found that the total botgehalte of people who drank milk compared with people who drank no milk, significantly with 40.32 grams [95% CI = 17.58 to 63.05] increased.

The researchers found that the NTx-content in the urine of people who drank milk compared with people who drank no milk, significantly with 5.41 nmol/mmol [95% CI =-10.35 to-0.47] reduced.

The researchers found that the total bone density of people who drank milk compared with people who drank no milk, significantly with 0.01 g/cm2 [95% CI =-0.02 to 0.03] increased, with a bordeline significance.

The researchers concluded that drinking milk (330 ml per day) to inhibit bone loss significantly weakened by the bone metabolism.

Original title:
Milk intake increases bone mineral content through inhibiting bone resorption: Meta-analysis of randomized controlled trials by Maa DF, Zhengb W, [...], W PY.

Link:
http://www.e-spenjournal.org/article/S2212-8263%2812%2900055-3/fulltext

Additional information about El Mondo:
The Osteocalcin is a substance that in the osteoblasts (bone cells that create the new bone) is made. The osteocalcinegehalte in the blood is related to the bone formation. In osteoporosis caused by an insufficient bone formation, the osteocalcinegehalte in the blood is reduced.

The hydroxyproline-, beta-CTx-and NTx-content in the urine reflect the degree of bone destruction.

The dairy recommendation in Netherlands is 450 ml (milk + dairy drink) per day. Read more about calcium.