Nutritional Advice El Mondo
Objectives:
Is there a causal relationship between grape product supplementation and improved lipid profiles in adults?
Study design:
This review article included 48 RCTs.
Results and conclusions:
The investigators found meta-analysis indicated that consumption of grape products significantly reduced the concentration of total cholesterol [MD = -6.196 mg/dL, 95% CI = -9.203 to -3.189], low-density lipoprotein cholesterol (bad cholesterol) [MD = -4.964 mg/dL, 95% CI = -7.594 to -2.334] and triglyceride [MD = -7.641 mg/dL, 95% CI = -12.120 to -3.162].
The investigators found grape product supplementation changed the HDL and LDL in a non-linear fashion based on the dose of polyphenols.
The investigators concluded that grape products have a favorable role in the achievement of a lipid profile target in adults, particularly total cholesterol, low-density lipoprotein cholesterol (bad cholesterol) and triglyceride levels.
Original title:
Effects of grape products on blood lipids: a systematic review and dose-response meta-analysis of randomized controlled trials by Ghaedi E, Moradi S, [...], Mohammadi H.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/31517353
Additional information of El Mondo:
Find more information/studies on fruits, meta-analysis and cholesterol right here.