Objectives:
Whether mushroom consumption, which is a rich source of potent antioxidants ergothioneine and glutathione, vitamins and minerals (e.g., selenium & copper), is associated with a lower mortality risk is not well understood. Therefore, this review article (meta-analysis) has been conducted.

Does mushroom consumption reduce all-cause mortality?

Objectives:
What is the effectiveness and safety of COVID-19 vaccines in the real world?

Study design:
This review article included 58 studies (32 studies for vaccine effectiveness and 26 studies for vaccine safety).

Objectives:
The relation between sodium intake and cardiovascular disease remains controversial, owing in part to inaccurate assessment of sodium intake. Assessing 24-hour urinary excretion over a period of multiple days is considered to be an accurate method. Therefore, this review article has been conducted.

Objectives:
What is the prevalence of insufficient iodine intake in pregnant women from different regions of the world?

Study design:
This review article included 61 observational articles with a total of 163,021 pregnant women adults and adolescents.

Results and conclusions:
The investigators found the overall prevalence of insufficient iodine intake was 53% [95% CI = 47 to 60, I2 = 99.8%].

Objectives:
Coronavirus disease 2019 (COVID-19), a global pandemic, has caused over 216 million cases and 4.50 million deaths as of 30 August 2021. Vaccines can be regarded as one of the most powerful weapons to eliminate the pandemic, but the impact of vaccines on daily COVID-19 cases and deaths by country is unclear. Therefore, this review articles has been conducted.

Objectives:
Leg cramps are one of the common symptoms during pregnancy. About 30%-50% of pregnant women experience leg cramps twice a week. Leg cramps may cause severe pain and sleep disturbance, hinder performance of daily activities and may lengthen the duration of pregnancy and the type of childbirth. Therefore, this review article has been conducted.

Does oral magnesium supplementation reduce leg cramps during pregnancy?

Objectives:
The efficacy of dendritic cell vaccine for newly diagnosed glioblastoma remains controversial. Therefore, this review article has been conducted.

Does dendritic cell vaccine provide benefits for the newly diagnosed glioblastoma?

Study design:
This review article included 3 randomized controlled trials (RCTs).

Objectives:
With the increasing incidence of osteoporosis, vitamin K and calcium have been linked to bone mineral density (BMD) and undercarboxylated osteocalcin (UcOC) in many studies, but the results of studies of the combined effect of vitamin K and calcium on BMD and UcOC in humans have been inconsistent. Therefore, this review article has been conducted.

Do vitamin K and calcium supplements used in combination increase bone mineral density and decrease undercarboxylated osteocalcin level?

Objectives:
Chemotherapy-induced peripheral neuropathy (CIPN) is a common symptom, but prophylactic measures cannot still be carried out effectively. In addition, the efficacy of vitamin E in preventing peripheral neurotoxicity caused by chemotherapy is inconclusive. Therefore, this review article has been conducted.

Objectives:
What is the proportion of asymptomatic cases among COVID-19 infections?

Study design:
This review article included 241 studies performed in 36 countries with a total of 130,123 ascertained COVID-19 infections, of which 31,411 asymptomatic infections.

Approximately 72.9% (175 out of 241) of all included studies were conducted in Asia, 11.7% in Europe and 10.42% in America.
In terms of study population, 80.5% were performed in general adults, 12.4% in children and 7.1% in pregnant women.